Molecular overlap links tuberous sclerosis, fragile X
Low in protein: Shank2 protein levels (red) are decreased in cerebellar cells from mice lacking TSC1. Brain cells from the cerebellums of mice that model tuberous sclerosis complex (TSC) show dampened protein levels, according to a new study. The affected proteins’ levels are controlled by FMRP, the protein missing in people with fragile X syndrome — a result that…